Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos

Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos

Background/Aims: Aberrantly high levels of H3K4me3, caused by incomplete epigenetic reprogramming, likely cause a low efficiency of somatic cell nuclear transfer (SCNT). Smal molecule inhibitors aimed at epigenetic modification can be used to improve porcine SCNT embryo development. In this study, w...

Full description

Bibliographic Details
Main Authors: Zhiren Zhang, Yanhui Zhai, Xiaoling Ma, Sheng Zhang, Xinglan An, Hao Yu, Ziyi Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
H3K4me3
MM-102
Epigenetic reprogramming
Somatic cell nuclear transfer
Online Access:https://www.karger.com/Article/FullText/487579

Internet

https://www.karger.com/Article/FullText/487579

Similar Items