Vismodegib for Locally Advanced Periocular and Orbital Basal Cell Carcinoma: A Review of 15 Consecutive Cases

Summary:. Basal cell carcinoma (BCC) is the most common periocular skin cancer and can lead to significant morbidity. We assess the effectiveness of vismodegib, a first-in-class Hedgehog signaling pathway inhibitor, in the management of periocular and orbital BCCs based on clinical response, tolerab...

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Main Authors: Kai Yuen Wong, MA, MRCS, Kate Fife, MD, FRCP, FRCR, John T. Lear, MD, FRCP, Richard D. Price, MD, FRCS (Plast), Amer J. Durrani, MSc, FRCS (Plast)
Format: Article
Language:English
Published: Wolters Kluwer 2017-07-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001424