I1 imidazoline receptor: novel potential cytoprotective target of TVP1022, the S-enantiomer of rasagiline.

TVP1022, the S-enantiomer of rasagiline (Azilect®) (N-propargyl-1R-aminoindan), exerts cyto/cardio-protective effects in a variety of experimental cardiac and neuronal models. Previous studies have demonstrated that the protective activity of TVP1022 and other propargyl derivatives involve the activ...

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Bibliographic Details
Main Authors: Yaron D Barac, Orit Bar-Am, Esti Liani, Tamar Amit, Luba Frolov, Elena Ovcharenko, Itzchak Angel, Moussa B H Youdim, Ofer Binah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23166584/pdf/?tool=EBI