Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

Using spheroids as a model, the authors report the molecular signatures of ovarian surface epithelial (OSE) cells exhibiting stemness phenotype under various conditions in vitro, and found that there is a large degree of heterogeneity in the transcriptional profiles of stem cells induced under diffe...

Full description

Bibliographic Details
Main Authors: Lauren E. Carter, David P. Cook, Curtis W. McCloskey, Melanie A. Grondin, David A. Landry, Tiffany Dang, Olga Collins, Lisa F. Gamwell, Holly A. Dempster, Barbara C. Vanderhyden
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02045-w