Angiogenin promotes U87MG cell proliferation by activating NF-κB signaling pathway and downregulating its binding partner FHL3.

Angiogenin (Ang) is known to induce cell proliferation and inhibit apoptosis by cellular signaling pathways and its direct nuclear functions, but the mechanism of action for Ang in astrocytoma is not yet clear. Astrocytoma is the most frequent one among various neurogliomas, of which a subtype known...

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Bibliographic Details
Main Authors: Wenrong Xia, Wenliang Fu, Xin Cai, Min Wang, Huihua Chen, Weiwei Xing, Yuanyuan Wang, Minji Zou, Tao Xu, Donggang Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4320115?pdf=render