Picturing Breast Cancer Brain Metastasis Development to Unravel Molecular Players and Cellular Crosstalk

Picturing Breast Cancer Brain Metastasis Development to Unravel Molecular Players and Cellular Crosstalk

With breast cancer (BC) therapy improvements, the appearance of brain metastases has been increasing, representing a life-threatening condition. Brain metastasis formation involves BC cell (BCC) extravasation across the blood–brain barrier (BBB) and brain colonization by unclear mechanisms. We aimed...

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Bibliographic Details
Main Authors: Inês Figueira, Sofia Galego, Tânia Custódio-Santos, Raquel Vicente, Kinga Molnár, Janos Haskó, Rui Malhó, Mafalda Videira, Imola Wilhelm, István Krizbai, Maria Alexandra Brito
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
blood–brain barrier
breast cancer brain metastasis
extravasation
intercellular communication
mesenchymal–epithelial transition
microvasculature
Online Access:https://www.mdpi.com/2072-6694/13/4/910

Internet

https://www.mdpi.com/2072-6694/13/4/910

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