Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells

Microgravity exerts dramatic effects on cell morphology and functions, by disrupting cytoskeleton and adhesion structures, as well as by interfering with biochemical pathways and gene expression. Impairment of cells behavior has both practical and theoretical significance, given that investigations...

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Bibliographic Details
Main Authors: Maria Grazia Masiello, Alessandra Cucina, Sara Proietti, Alessandro Palombo, Pierpaolo Coluccia, Fabrizio D’Anselmi, Simona Dinicola, Alessia Pasqualato, Veronica Morini, Mariano Bizzarri
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/652434