Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2−/− mice

Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2−/− mice

Charcot–Marie–Tooth neuropathies are frequent hereditary disorders of the nervous system and most cases remain without a molecular definition. Mutations in transcription factors have been previously associated to various types of this disease. Mice carrying a null mutation in Ebf2 transcription fact...

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Bibliographic Details
Main Authors: Caterina Giacomini, Veronica La Padula, Angelo Schenone, Massimo Leandri, Andrea Contestabile, Diego Moruzzo, Laurence Goutebroze, G. Giacomo Consalez, Fabio Benfenati, Anna Corradi
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Neurobiology of Disease
Subjects:
Ebf2−/− mice
Peripheral neuropathy
Myelin
Motor conduction velocity
Transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000076

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http://www.sciencedirect.com/science/article/pii/S0969996111000076

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