Mitochondrial D-Loop Region Methylation and Copy Number in Peripheral Blood DNA of Parkinson’s Disease Patients

Mitochondrial D-Loop Region Methylation and Copy Number in Peripheral Blood DNA of Parkinson’s Disease Patients

Altered mitochondrial DNA (mtDNA) methylation has been detected in several human pathologies, although little attention has been given to neurodegenerative diseases. Recently, altered methylation levels of the mitochondrial displacement loop (D-loop) region, which regulates mtDNA replication, were o...

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Bibliographic Details
Main Authors: Andrea Stoccoro, Adam R. Smith, Filippo Baldacci, Claudia Del Gamba, Annalisa Lo Gerfo, Roberto Ceravolo, Katie Lunnon, Lucia Migliore, Fabio Coppedè
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
Mitoepigenetics
DNA methylation
D-loop region
Parkinson’s disease
Online Access:https://www.mdpi.com/2073-4425/12/5/720

Internet

https://www.mdpi.com/2073-4425/12/5/720

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