Pharmacokinetics of an injectable long-acting formulation of doxycycline hyclate in dogs

Pharmacokinetics of an injectable long-acting formulation of doxycycline hyclate in dogs

<p>Abstract</p> <p>Based on its PK/PD ratios, doxycycline hyclate (DOX-h), a time-dependant antibacterial, is ideally expected to achieve both sustained plasma drug concentrations at or slightly above the MIC level for as long as possible between dosing intervals. Pursuing this end...

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Bibliographic Details
Main Authors: Gutiérrez Lilia, Velasco Zazil-Ha, Vázquez Carlos, Vargas Dinorah, Sumano Héctor
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Acta Veterinaria Scandinavica
Subjects:
Doxycycline
Dog
Pharmacokinetics
Long-acting
Poloxamer
β-cyclodextrin
Online Access:http://www.actavetscand.com/content/54/1/35

Internet

http://www.actavetscand.com/content/54/1/35

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