Tumor Antigen-Dependent and Tumor Antigen-Independent Activation of Antitumor Activity in T Cells by a Bispecific Antibody-Modified Tumor Vaccine

New approaches of therapeutic cancer vaccination are needed to improve the antitumor activity of T cells from cancer patients. We studied over the last years the activation of human T cells for tumor attack. To this end, we combined the personalized therapeutic tumor vaccine ATV-NDV—which is obtaine...

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Bibliographic Details
Main Authors: Philippe Fournier, Volker Schirrmacher
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2010/423781