A 3‐week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death

The long duration of animal models represents a clear limitation to quickly evaluate the efficacy of drugs targeting nonalcoholic steatohepatitis (NASH). We, therefore, developed a rapid mouse model of liver inflammation (i.e., the mouse fed a high‐fat/high‐cholesterol diet, where cyclodextrin is co...

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Bibliographic Details
Main Authors: François Briand, Christophe Heymes, Lucile Bonada, Thibault Angles, Julie Charpentier, Maxime Branchereau, Emmanuel Brousseau, Marjolaine Quinsat, Nicolas Fazilleau, Rémy Burcelin, Thierry Sulpice
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12735