Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells.

Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells.

Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and possess anti-tumor activity. Here, we examined icaritin effect on cell growth of human endometrial cancer Hec1A cells and found that icaritin potently inhibited proliferation of Hec1A cells. Ic...

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Bibliographic Details
Main Authors: Jing-Shan Tong, Qing-Hua Zhang, Xin Huang, Xue-Qi Fu, Shu-Tao Qi, Ya-Peng Wang, Yi Hou, Jun Sheng, Qing-Yuan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3050810?pdf=render

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http://europepmc.org/articles/PMC3050810?pdf=render

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