Renal failure during chemotherapy: renal biopsy for assessing subacute nephrotoxicity of pemetrexed

Abstract Background Pemetrexed, a multitargeted antifolate cytotoxic agent, is currently used primarily in combination with cisplatin for metastatic non-small cell lung cancer and for malignant mesothelioma. Acute renal toxicity of pemetrexed has been recently described with polychemotherapy, in whi...

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Bibliographic Details
Main Authors: Maureen Assayag, Philippe Rouvier, Marion Gauthier, Ghania Costel, Philippe Cluzel, Lucile Mercadal, Gilbert Deray, Corinne Isnard Bagnis
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Online Access:http://link.springer.com/article/10.1186/s12885-017-3705-7