Non-Invasive Detection of Extracellular Matrix Metalloproteinase Inducer EMMPRIN, a New Therapeutic Target against Atherosclerosis, Inhibited by Endothelial Nitric Oxide

Non-Invasive Detection of Extracellular Matrix Metalloproteinase Inducer EMMPRIN, a New Therapeutic Target against Atherosclerosis, Inhibited by Endothelial Nitric Oxide

Lack of endothelial nitric oxide causes endothelial dysfunction and circulating monocyte infiltration, contributing to systemic atheroma plaque formation in arterial territories. Among the different inflammatory products, macrophage-derived foam cells and smooth muscle cells synthesize matrix metall...

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Bibliographic Details
Main Authors: Rafael Ramirez-Carracedo, Laura Tesoro, Ignacio Hernandez, Javier Diez-Mata, Marco Filice, Rocío Toro, Manuel Rodriguez-Piñero, Jose Luis Zamorano, Marta Saura, Carlos Zaragoza
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
nitric oxide
endothelial nitric oxide synthase
metalloproteinsases
nanoparticles
magnetic resonance imaging
extacellular matrix metalloproteinase inducer EMMPRIN
Online Access:http://www.mdpi.com/1422-0067/19/10/3248

Internet

http://www.mdpi.com/1422-0067/19/10/3248

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