Epidermal growth factor receptor inhibitor AG1478 affects HepG2 cell proliferation, cell cycle, apoptosis and c-Myc protein expression in a dose-dependent manner

The aim of this study was to observe the effect of AG1478, an inhibitor of the epidermal growth factor receptor, on cell proliferation, cell cycle and apoptosis of human hepatoma HepG2 cells. Cell counting kit-8 assay was employed to examine the survival rates of cultured HepG2 cells after treatment...

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Bibliographic Details
Main Authors: Wenqi Wang, Mingxian Yan, Changhong Liu, Yiguo Wang, Yaru Wang, Liyun Wang, Jinhua Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2018.1460620