Persistent platelet activation and apoptosis in virologically suppressed HIV-infected individuals

Persistent platelet activation and apoptosis in virologically suppressed HIV-infected individuals

Abstract Cardiovascular diseases and thrombotic events became major clinical problems in the combined antiretroviral therapy (cART) era. Although the precise mechanisms behind these clinical problems have not been fully elucidated, a persistent pro-inflammatory state plays a central role. As platele...

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Bibliographic Details
Main Authors: Emersom C. Mesquita, Eugenio D. Hottz, Rodrigo T. Amancio, Alan B. Carneiro, Lohanna Palhinha, Lara E. Coelho, Beatriz Grinsztejn, Guy A. Zimmerman, Matthew T. Rondina, Andrew S. Weyrich, Patrícia T. Bozza, Fernando A. Bozza
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Increased Platelet Activation
Virologic Suppression
RANTES Secretion
Stable cART
Platelet Spreading
Online Access:https://doi.org/10.1038/s41598-018-33403-0

Internet

https://doi.org/10.1038/s41598-018-33403-0

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