Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an <i>In-Silico</i> Approach

Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an <i>In-Silico</i> Approach

Single-nucleotide polymorphisms (SNPs) are reported to be associated with many diseases, including autoimmune diseases. In rheumatoid arthritis (RA), about 152 SNPs are reported to account for ~15% of its heritability. These SNPs may result in the alteration of gene expression and may also affect th...

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Bibliographic Details
Main Authors: Mehran Akhtar, Yasir Ali, Zia-ul Islam, Maria Arshad, Mamoona Rauf, Muhammad Ali, Saleh N. Maodaa, Saleh A. Al-Farraj, Hamed A. El-Serehy, Fazal Jalil
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biology
Subjects:
SNPs
rheumatoid arthritis
miRNA
gene–gene interaction
therapeutic sites
Online Access:https://www.mdpi.com/2079-7737/10/6/501

Internet

https://www.mdpi.com/2079-7737/10/6/501

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