The tetraspanins CD9 and CD81 regulate CD9P1-induced effects on cell migration.

CD9P-1 is a cell surface protein with immunoglobulin domains and an unknown function that specifically associates with tetraspanins CD9 and CD81. Overexpression of CD9P-1 in HEK-293 cells induces dramatic changes in cell spreading and migration on various matrices. Experiments using time-lapse video...

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Bibliographic Details
Main Authors: Célia Chambrion, François Le Naour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2888588?pdf=render