Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths
The activation of 2'-5'-oligoadenylate synthetase (OAS) enzymes by direct interaction with viral double-stranded RNA (dsRNA) is a key part of the innate immune response to viral infection. A downstream effect of the OAS-dsRNA interaction is to degrade the single-stranded RNA to prevent the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2021-04-01
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| Series: | AIMS Mathematics |
| Subjects: | |
| Online Access: | http://www.aimspress.com/article/doi/10.3934/math.2021351?viewType=HTML |