Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis.

Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder that may develop after an individual has experienced or witnessed a severe traumatic event. It has been shown that the 18 kDa translocator protein (TSPO) may be correlated with PTSD and that the TSPO ligand improved the behavio...

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Bibliographic Details
Main Authors: Yu-Liang Miao, Wen-Zhi Guo, Wen-Zhu Shi, Wei-Wu Fang, Yan Liu, Ji Liu, Bao-Wei Li, Wei Wu, Yun-Feng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079590?pdf=render