In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum

In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum

Objectives: Eravacycline is a novel synthetic halogenated tetracycline derivative with a broad antibacterial spectrum. Antibiotics, including tetracyclines, have been used for prophylaxis and, more rarely, for the treatment of malaria for several decades. The rise in drug-resistant malaria parasites...

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Bibliographic Details
Main Authors: Erik Koehne, Andrea Kreidenweiss, Bayode Romeo Adegbite, Rella Zoleko Manego, Matthew B.B. McCall, Ghyslain Mombo-Ngoma, Ayola Akim Adegnika, Sélidji Todagbé Agnandji, Benjamin Mordmüller, Jana Held
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Plasmodium falciparum
Eravacycline
Tetracycline
Isopentenyl pyrophosphate
Malaria
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716520303106

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http://www.sciencedirect.com/science/article/pii/S2213716520303106

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