The novel ortho-chloro derivate propafenone induced relaxation in isolated rat aorta

The information on the inhibitory effect of propafenone in vascular smooth muscle is sparse. Propafenone acts through blockage of voltage-dependent cardiac Na+ channels, L-type Ca2+ channels, voltage-sensitive K+ (Kv) channels, as well as β-adrenergic receptors in the heart. The introduction of...

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Bibliographic Details
Main Authors: Ivković Branka, Gojković-Bukarica Ljiljana, Vladimirov S., Radmila Novaković, Ćupić V., Lešić A., Bumbaširević M., Šćepanović R.
Format: Article
Language:English
Published: Sciendo 2013-01-01
Series:Acta Veterinaria
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0567-8315/2013/0567-83151304363I.pdf