Mouse Systems to Model Hepatitis C Virus Treatment and Associated Resistance

Mouse Systems to Model Hepatitis C Virus Treatment and Associated Resistance

While addition of the first-approved protease inhibitors (PIs), telaprevir and boceprevir, to pegylated interferon (PEG-IFN) and ribavirin (RBV) combination therapy significantly increased sustained virologic response (SVR) rates, PI-based triple therapy for the treatment of chronic hepatitis C viru...

Full description

Bibliographic Details
Main Authors: Ahmed Atef Mesalam, Koen Vercauteren, Philip Meuleman
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Viruses
Subjects:
HCV
animal models
therapy
direct acting antiviral agents
humanized mice
resistance
deep sequencing
Online Access:http://www.mdpi.com/1999-4915/8/6/176

Internet

http://www.mdpi.com/1999-4915/8/6/176

Similar Items