Tumor necrosis factor receptor signaling modulates carcinogenesis in a mouse model of breast cancer

Pro-inflammatory conditions have long been associated with mammary carcinogenesis and breast cancer progression. The underlying mechanisms are incompletely understood but signaling of pro-inflammatory cytokine TNFα through its receptors TNFR1 and TNFR2 is a major mediator of inflammation in both obe...

Full description

Bibliographic Details
Main Authors: Ling He, Kruttika Bhat, Sara Duhacheck-Muggy, Angeliki Ioannidis, Le Zhang, Nhan T. Nguyen, Neda A. Moatamed, Frank Pajonk
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301883