The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach

The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach

Fibroblast growth factors (FGFs) play non-redundant autocrine/paracrine functions in various human cancers. The Cancer Genome Atlas (TCGA) data mining indicates that high levels of FGF and/or FGF receptor (FGFR) expression are associated with reduced overall survival, chromosome 3 monosomy and <i...

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Bibliographic Details
Main Authors: Sara Rezzola, Roberto Ronca, Alessandra Loda, Mohd Imtiaz Nawaz, Chiara Tobia, Giuseppe Paganini, Federica Maccarinelli, Arianna Giacomini, Francesco Semeraro, Marco Mor, Marco Presta
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
FGF
FGF receptors
liver metastasis
tumor grafts
uveal melanoma
zebrafish
Online Access:https://www.mdpi.com/2072-6694/11/9/1305

Internet

https://www.mdpi.com/2072-6694/11/9/1305

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