Salt potentiates methylamine counteraction system to offset the deleterious effects of urea on protein stability and function.

Cellular methylamines are osmolytes (low molecular weight organic compounds) believed to offset the urea's harmful effects on the stability and function of proteins in mammalian kidney and marine invertebrates. Although urea and methylamines are found at 2:1 molar ratio in tissues, their opposi...

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Bibliographic Details
Main Authors: Safikur Rahman, Md Tabish Rehman, Laishram R Singh, Marina Warepam, Faizan Ahmad, Tanveer Ali Dar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368626?pdf=render