Activation of CamKIIα expressing neurons on ventrolateral periaqueductal gray improves behavioral hypersensitivity and thalamic discharge in a trigeminal neuralgia rat model

Activation of CamKIIα expressing neurons on ventrolateral periaqueductal gray improves behavioral hypersensitivity and thalamic discharge in a trigeminal neuralgia rat model

Abstract Background Preceding studies have reported the association of chronic neuropathic orofacial pain with altered ongoing function in the ventrolateral periaqueductal gray (vlPAG). However, its role in trigeminal neuralgia (TN) lacks attention. We here reported the aspect that vlPAG neurons pla...

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Bibliographic Details
Main Authors: K. C. Elina, Byeong Ho Oh, Jaisan Islam, Soochong Kim, Young Seok Park
Format: Article
Language:English
Published: BMC 2021-05-01
Series:The Journal of Headache and Pain
Subjects:
Microdialysis
Optogenetics
Periaqueductal gray
Thalamus
Trigeminal neuralgia
Online Access:https://doi.org/10.1186/s10194-021-01257-z

Internet

https://doi.org/10.1186/s10194-021-01257-z

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