HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy

HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy

Background The human leucocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Understanding the benign HLA ligand repertoire is a prerequisite to define safe T-cell-based immunotherapies against...

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Bibliographic Details
Main Authors: Jian Wang, Michael Weller, Roland Martin, Holger Moch, Julia Velz, Luca Regli, Hans-Georg Rammensee, Linus Backert, Oliver Kohlbacher, Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Lena Mühlenbruch, András Szolek, Maren Lübke, Philipp Wagner, Tobias Engler, Sabine Matovina, Mathias Hauri-Hohl, Konstantina Kapolou, Juliane Sarah Walz, Manuela Silginer, Markus W. Löffler, Florian Erhard, Andreas Schlosser, Stefan Stevanović, Marian Christoph Neidert
Format: Article
Language:English
Published: BMJ Publishing Group 2021-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/4/e002071.full

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https://jitc.bmj.com/content/9/4/e002071.full

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