In vivo quantification of neurofibrillary tangles with [18F]MK-6240

In vivo quantification of neurofibrillary tangles with [18F]MK-6240

Abstract Background Imaging agents capable of quantifying the brain’s tau aggregates will allow a more precise staging of Alzheimer’s disease (AD). The aim of the present study was to examine the in vitro properties as well as the in vivo kinetics, using gold standard methods, of the novel positron...

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Bibliographic Details
Main Authors: Tharick A. Pascoal, Monica Shin, Min Su Kang, Mira Chamoun, Daniel Chartrand, Sulantha Mathotaarachchi, Idriss Bennacef, Joseph Therriault, Kok Pin Ng, Robert Hopewell, Reda Bouhachi, Hung-Hsin Hsiao, Andrea L. Benedet, Jean-Paul Soucy, Gassan Massarweh, Serge Gauthier, Pedro Rosa-Neto
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Tau positron emission tomography
Neurofibrillary tangles
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13195-018-0402-y

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http://link.springer.com/article/10.1186/s13195-018-0402-y

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