PB01 suppresses radio-resistance by regulating ATR signaling in human non-small-cell lung cancer cells

Abstract Despite the common usage of radiotherapy for the treatment of human non-small-cell lung cancer (NSCLC), cancer therapeutic efficacy and outcome with ionizing radiation remains a challenge. Here, we report the antitumor effects and mechanism of a novel benzothiazole derivative PB01 (4-methox...

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Bibliographic Details
Main Authors: Tae Woo Kim, Da-Won Hong, Sung Hee Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91716-z