Bubbles Induce Endothelial Microparticle Formation via a Calcium-Dependent Pathway Involving Flippase Inactivation and Rho Kinase Activation

Bubbles Induce Endothelial Microparticle Formation via a Calcium-Dependent Pathway Involving Flippase Inactivation and Rho Kinase Activation

Background/Aims: Intravascular bubbles can exert pleiotropic detrimental effects, partly by inducing endothelial microparticles (EMPs) production, which play critical roles in cell communication and vascular inflammation cascades. However, the underlying mechanisms remain unclear. This study aimed t...

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Bibliographic Details
Main Authors: Xuhua Yu, Jiajun Xu, Wenwu Liu, Weigang Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Bubble
Endothelial microparticles
Calcium
Rho kinase
Flippase
Online Access:https://www.karger.com/Article/FullText/488825

Internet

https://www.karger.com/Article/FullText/488825

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