Detection of Hepatitis C Virus Core Protein in Serum Using Aptamer-Functionalized AFM Chips

Detection of Hepatitis C Virus Core Protein in Serum Using Aptamer-Functionalized AFM Chips

In the present study, we demonstrate atomic force microscopy (AFM)-based detection of hepatitis C virus (HCV) particles in serum samples using a chip with aptamer-functionalized surface (apta-based AFM chip). The target particles, containing core antigen of HCV (HCVcoreAg protein), were biospecifica...

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Bibliographic Details
Main Authors: Tatyana O. Pleshakova, Anna L. Kaysheva, Ivan D. Shumov, Vadim S. Ziborov, Jana M. Bayzyanova, Vladimir A. Konev, Vasiliy F. Uchaikin, Alexander I. Archakov, Yuri D. Ivanov
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Micromachines
Subjects:
atomic force microscopy
aptamer
protein detection
viral hepatitis
mass spectrometry
Online Access:https://www.mdpi.com/2072-666X/10/2/129

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https://www.mdpi.com/2072-666X/10/2/129

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