Stochastic model of Tsc1 lesions in mouse brain.

Stochastic model of Tsc1 lesions in mouse brain.

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder due to mutations in either TSC1 or TSC2 that affects many organs with hamartomas and tumors. TSC-associated brain lesions include subependymal nodules, subependymal giant cell astrocytomas and tubers. Neurologic manifestations in TSC...

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Bibliographic Details
Main Authors: Shilpa Prabhakar, June Goto, Xuan Zhang, Miguel Sena-Esteves, Roderick Bronson, Jillian Brockmann, Davide Gianni, Gregory R Wojtkiewicz, John W Chen, Anat Stemmer-Rachamimov, David J Kwiatkowski, Xandra O Breakefield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3655945?pdf=render

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http://europepmc.org/articles/PMC3655945?pdf=render

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