Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice.

Heterotopic or aberrantly positioned cortical neurons are associated with epilepsy and intellectual disability. Various mouse models exist with forms of heterotopia, but the composition and state of cells developing in heterotopic bands has been little studied. Dcx knockout (KO) mice show hippocampa...

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Main Authors: Reham Khalaf-Nazzal, Elodie Bruel-Jungerman, Jean-Paul Rio, Jocelyne Bureau, Theano Irinopoulou, Iffat Sumia, Audrey Roumegous, Elodie Martin, Robert Olaso, Carlos Parras, Carmen Cifuentes-Diaz, Fiona Francis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24023755/pdf/?tool=EBI