Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

A genetic risk score (GRS) was developed for predicting fracture risk based on the prevalence of vertebral fractures in 441 Japanese females with osteoporosis. A total of 979 (858 nonsynonymous and 121 silent) single-nucleotide polymorphisms (SNPs) located in 74 osteoporosis-susceptibility genes wer...

Full description

Bibliographic Details
Main Authors: Heying Zhou, Seijiro Mori, Tatsuro Ishizaki, Atsushi Takahashi, Koichi Matsuda, Yukihiro Koretsune, Shiro Minami, Masahiko Higashiyama, Shinji Imai, Kozo Yoshimori, Minoru Doita, Akira Yamada, Satoshi Nagayama, Kazuo Kaneko, Satoshi Asai, Masaki Shiono, Michiaki Kubo, Hideki Ito
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187216300250

Internet

http://www.sciencedirect.com/science/article/pii/S2352187216300250

Similar Items