An (R)-Selective Transaminase From Thermomyces stellatus: Stabilizing the Tetrameric Form

An (R)-Selective Transaminase From Thermomyces stellatus: Stabilizing the Tetrameric Form

The identification and 3D structural characterization of a homolog of the (R)-selective transaminase (RTA) from Aspergillus terreus (AtRTA), from the thermotolerant fungus Thermomyces stellatus (TsRTA) is here reported. The thermostability of TsRTA (40% retained activity after 7 days at 40°C) was in...

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Bibliographic Details
Main Authors: Christian M. Heckmann, Louise J. Gourlay, Beatriz Dominguez, Francesca Paradisi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
biocatalysis
amino transferase
crystal structure
chiral amine
thermostability
quaternary structure
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00707/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00707/full

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