Twist-2 controls myeloid lineage development and function.

Basic helix-loop-helix (bHLH) transcription factors play critical roles in lymphoid and erythroid development; however, little is known about their role in myeloid lineage development. In this study, we identify the bHLH transcription factor Twist-2 as a key negative regulator of myeloid lineage dev...

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Bibliographic Details
Main Authors: Andrew B Sharabi, Melissa Aldrich, Drazen Sosic, Eric N Olson, Alan D Friedman, Sung-Hyung Lee, Si-Yi Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2602725?pdf=render