Wnt-inducible protein (WISP-1) is a key regulator of alveolar epithelial cell hyperplasia in pulmonary fibrosis

Fibrotic lung disease is characterized by distorted lung architecture and severe loss of respiratory function secondary to alveolar epithelial cell (AEC) hyperplasia, enhanced extracellular matrix (ECM) deposition and fibroblast proliferation. Repetitive epithelial injuries with impaired alveolar wo...

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Bibliographic Details
Main Authors: Melanie Königshoff, Jochen Wilhelm, Andreas Jahn, Oana Amarie, Kamila Kitowska, Anke Wilhelm, Rainer. M. Bohle, Werner Seeger, Frank Rose, Ludger Fink, Andreas Guenther, Oliver Eickelberg
Format: Article
Language:English
Published: European Respiratory Society 2006-12-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/cgi/content/full/15/101/180