The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders

Abstract The endoplasmic reticulum (ER) is the biggest organelle in cells and is involved in versatile cellular processes. Formation and maintenance of ER morphology are regulated by a series of proteins controlling membrane fusion and curvature. At least six different ER morphology regulators have...

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Bibliographic Details
Main Authors: Yu-Tzu Shih, Yi-Ping Hsueh
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-017-0403-3