Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet.

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet.

To investigate therapeutic effects of annexin A1 (anxA1) on atherogenesis in LDLR-/- mice.Human recombinant annexin A1 (hr-anxA1) was produced by a prokaryotic expression system, purified and analysed on phosphatidylserine (PS) binding and formyl peptide receptor (FPR) activation. Biodistribution of...

Full description

Bibliographic Details
Main Authors: Dennis H M Kusters, Martijn L Chatrou, Brecht A G Willems, Marijke De Saint-Hubert, Matthias Bauwens, Emiel van der Vorst, Stefania Bena, Erik A L Biessen, Mauro Perretti, Leon J Schurgers, Chris P M Reutelingsperger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4475013?pdf=render

Internet

http://europepmc.org/articles/PMC4475013?pdf=render

Similar Items