In silico reconstruction and experimental validation of Saccharopolyspora erythraea genome-scale metabolic model iZZ1342 that accounts for 1685 ORFs

Abstract Background Saccharopolyspora erythraea (S. erythraea) is a Gram-positive erythromycin–producing filamentous bacterium. The lack of comprehensive S. erythraea genome-scale metabolic models (GEMs) hinders the efficiency of metabolic engineering as well as fermentation process optimization. Re...

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Bibliographic Details
Main Authors: Zhendong Zhuang, Mingzhi Huang, Ju Chu
Format: Article
Language:English
Published: SpringerOpen 2018-06-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40643-018-0212-x