Selective localization of IgG from cerebrospinal fluid to brain parenchyma
Abstract Background Encounter of autoantibodies with specific antigens can lead to hypersensitivity reactions and pathology. In multiple sclerosis and neuromyelitis optica spectrum disease (NMOSD), immunoglobulin-G (IgG) deposition has been observed in pathological lesions in the central nervous sys...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1159-8 |