BDNF and the maturation of posttranscriptional regulatory networks in human SH-SY5Y neuroblast differentiation

BDNF and the maturation of posttranscriptional regulatory networks in human SH-SY5Y neuroblast differentiation

The SH-SY5Y culture system is a convenient neuronal model with the potential to elaborate human/primate-specific transcription networks and pathways related to human cognitive disorders. While this system allows for the exploration of specialised features in the human genome, there is still signific...

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Bibliographic Details
Main Authors: Belinda J Goldie, Michelle M Barnett, Murray J Cairns
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cell Culture Techniques
Gene Expression Profiling
MicroRNAs
neuronal differentiation
SH-SY5Y cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00325/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00325/full

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