Developmental role and regulation of cortex, a meiosis-specific anaphase-promoting complex/cyclosome activator.

During oogenesis in metazoans, the meiotic divisions must be coordinated with development of the oocyte to ensure successful fertilization and subsequent embryogenesis. The ways in which the mitotic machinery is specialized for meiosis are not fully understood. cortex, which encodes a putative femal...

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Bibliographic Details
Main Authors: Jillian A Pesin, Terry L Orr-Weaver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2077894?pdf=render