Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes.

Autophagy acts as a host-defense system against pathogenic microorganisms such as Group A Streptococcus (GAS). Autophagy is a membrane-mediated degradation system that is regulated by intracellular membrane trafficking regulators, including small GTPase Rab proteins. Here, we identified Rab30 as a n...

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Bibliographic Details
Main Authors: Seiichiro Oda, Takashi Nozawa, Atsuko Nozawa-Minowa, Misako Tanaka, Chihiro Aikawa, Hiroyuki Harada, Ichiro Nakagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4714835?pdf=render