Immunomodulatory Effect of Chymotrypsin in CNS Is Sex-independent: Evidence of Anti-inflammatory Role for IL-17 in EAE

Immunomodulatory Effect of Chymotrypsin in CNS Is Sex-independent: Evidence of Anti-inflammatory Role for IL-17 in EAE

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are inflammatory autoimmune diseases of the central nervous system. Chymotrypsin is a serine protease with immunomodulatory effect in the peripheral organs. We previously demonstrated the immunomodulatory...

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Bibliographic Details
Main Authors: Ameneh Ghaffarinia, Shahram Parvaneh, Cyrus Jalili, Farhad Riazi-Rad, Somayeh Yaslianifard, Nafiseh Pakravan
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-04-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Anti-inflammatory
Chymotrypsin
CNS
Experimental autoimmune encephalomyelitis
Immunomodulation
Interleukin-17
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/364

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/364

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