Immunomodulatory Effect of Chymotrypsin in CNS Is Sex-independent: Evidence of Anti-inflammatory Role for IL-17 in EAE
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are inflammatory autoimmune diseases of the central nervous system. Chymotrypsin is a serine protease with immunomodulatory effect in the peripheral organs. We previously demonstrated the immunomodulatory...
Main Authors: | Ameneh Ghaffarinia, Shahram Parvaneh, Cyrus Jalili, Farhad Riazi-Rad, Somayeh Yaslianifard, Nafiseh Pakravan |
---|---|
Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2016-04-01
|
Series: | Iranian Journal of Allergy, Asthma and Immunology |
Subjects: | |
Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/364 |
Similar Items
-
Kinetics of T cell response in the testes and CNS during experimental autoimmune encephalomyelitis: Simultaneous blood-brain and -testis barrier permeability?
by: Nafiseh Pakravan, et al.
Published: (2019-07-01) -
Kinetic and magnetic resonance studies of derivatized chymotrypsins /
by: Landis, Bryan Hayden
Published: (1976) -
Towards an #alpha#-chymotrypsin mimic and the 3-acetyltetramic acid erythroskyrine
by: Tankard, M.
Published: (1989) -
Temperature and kinetic isotope effect studies on 5 substituted furoyl-[alpha]-chymotrypsins /
by: Calvo, Kim C.
Published: (1981) -
Studies in the acyl enzyme of chymotrypsin : affects of substituent, pH, and temperature /
by: Moffit, Michael Joseph
Published: (1979)