I2/DMSO-Catalyzed Transformation of N-tosylhydrazones to 1,2,3-thiadiazoles

I2/DMSO-Catalyzed Transformation of N-tosylhydrazones to 1,2,3-thiadiazoles

An iodine/DMSO catalyzed selective cyclization of N-tosylhydrazones with sulfur without adding external oxidant was developed for the synthesis of 4-aryl-1,2,3-thiadiazoles. In this reaction, oxidation of HI by using DMSO as dual oxidant and solvent is the key, which allowed the regeneration of I2,...

Full description

Bibliographic Details
Main Authors: Weiwei Li, Jun Zhang, Jing He, Liang Xu, Luigi Vaccaro, Ping Liu, Yanlong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Chemistry
Subjects:
N-tosylhydrazone
1,2,3-thiadiazoles
iodine
DMSO
sulfur
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00466/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00466/full

Similar Items