Increasing coverage of transcription factor position weight matrices through domain-level homology.

Transcription factor-DNA interactions, central to cellular regulation and control, are commonly described by position weight matrices (PWMs). These matrices are frequently used to predict transcription factor binding sites in regulatory regions of DNA to complement and guide further experimental inv...

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Bibliographic Details
Main Authors: Brady Bernard, Vesteinn Thorsson, Hector Rovira, Ilya Shmulevich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428306?pdf=render